Taking a vacation in the Florida Keys is one of the most serene vacations you can have. Bright sunshine, great weather, and lots of fun can be had at one of the luxury resorts in the area.If you are looking for certain features of a resort or want lots of luxury, book your next stay at one of the luxury resorts in the Florida Keys from the list below. These best resorts in the Keys are based on the stars they have received and the amenities they offer their guests.