A red-eye flight departs late at night and lands early in the morning; it typically takes off after 9 p.m. and lands between 5 and 6 a.m. So, in taking a red-eye, you’ll be in the air overnight, when you would typically be asleep.There are certain proactive measures you may take if you’ve scheduled a red-eye flight to avoid the challenges that come with traveling overnight. A little planning can go a long way toward improving your flight’s comfort.