Just added this to my Flipboard. I was stung by a wasp a couple weeks ago, and that got the whole family discussing this topic. I'm still not sure I would know the difference if I come upon one suddenly.
There are definitely pros and cons to asynchronous communication. I find the pros vastly outweigh the cons, except for brainstorming and for handling emergencies. Those are two cons your article identifies. I don't think isolation and connection are big deals, as there are plenty of opportunities to connect with other people. Then again, I suppose I don't speak for extraverts.
It's amazing how useful hashtags are on Twitter , if you can find communities of interest. The numbers generally lie, though. It's about finding people who actually follow hashtags. They are still pretty useless on Facebook and LinkedIn, though.