A cat wheezing generally means the cat needs medical attention. There are a number of things that can cause the wheezing and not all of them are serious, but some are. The situation is generally more serious if the condition appears or be chronic, or at the very least fairly frequent. A one time occurrence, or a cat wheezing only in certain times or circumstances, is more apt to mean that something in the air, such as dust or pollen, may be irritating the cat, and it can be a transitory thing.